transferrin receptors การใช้

• These include transferrin receptor, D-beta-hydroxybutyrate dehydrogenase
• Transferrin receptor production depends on a similar mechanism.
• One arm had a low-affinity anti-transferrin receptor binding site that induces transcytosis.
• The cell stops producing transferrin receptors.
• That will stop transferrin receptor production.
• There is very high selectivity for transferrin receptors because they are over-expressed in cancer cells.
• In low-iron conditions, IRE-BPs allow the cell to keep producing transferrin receptors.
• The shape of a transferrin receptor resembles a butterfly based on the intersection of three clearly shaped domains.
• Cancer cells have much higher levels of transferrin receptors than normal cells and are very dependent on iron for their proliferation.
• It is thought that this protein functions to regulate circulating iron uptake by regulating the interaction of the transferrin receptor with transferrin.
• IGFBP-3 can enter cells by both clathrin-mediated and caveolin-mediated endocytosis . possibly involving the transferrin receptor.
• To date, the conventionally identified soluble transferrin receptor has not been itself implicated in intracellular delivery of transferrin and associated iron.
• And more transferrin receptors make it easier for the cell to bring in more iron from transferrin-iron complexes circulating outside the cell.
• The measurement of the soluble transferrin receptor ( sTfR ) is used as a measure of blood iron levels and the investigation of anemia.
• Sequences of mRNA called iron-responsive elements ( IREs ) are contained within the mRNA sequences that code for transferrin receptors and for ferritin.
• An increase in insulin levels also signals for the movement of transferrin receptors from the vesicles of insulin-sensitive cells to the plasma membrane.
• Testing of HeLa cells and human cells to exposure of both feline parvovirus and canine parvovirus resulted in infections of the cells at human transferrin receptors.
• Transferrin receptors in cancer cells, such as those in breast cancer cells and epithelial cervical cells, promote the cell proliferation and malignancy of the cancer.
• Although transferrin receptors may be limited on cell surfaces the parvovirus will find available transferrin receptors and will use different pathways to gain entry to the cell.
• Although transferrin receptors may be limited on cell surfaces the parvovirus will find available transferrin receptors and will use different pathways to gain entry to the cell.